Regulatory T cells in systemic lupus erythematosus
نویسندگان
چکیده
منابع مشابه
Regulatory T cells in systemic lupus erythematosus and pregnancy.
Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disorder that predominantly affects women of reproductive age. As clinical outcomes improve, pregnancy in these women is becoming more common. Although epidemiological data have documented an improvement in the prognosis of pregnancy in these women over recent years, they are still at significantly increased risk of pregnanc...
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Objective(s): Apoptosis is a tightly regulated process and plays a crucial role in autoimmune diseases. Because abnormalities in apoptosis are considered to be involved in the pathogenesis of systemic lupus erythematosus (SLE), in present study we studied the apoptosis in T lymphocytes from Iranian SLE patientsat protein and gene expression levels for some molecules which are involved in apopt...
متن کاملIntroduction: T cells and systemic lupus erythematosus
erythematosus Systemic lupus erythematosus (SLE) is an autoimmune disease that affl icts mainly women in the reproductive years. It is a multisystem disease aff ecting the joints, skin, kidneys and brain and is characterized by autoantibody production by dysregulated B cells, target organ infi ltration by infl ammatory T cells and aberrant immune cell activation due to abnormal antigen presenti...
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Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody production, complement activation, and immune complex deposition, resulting in tissue and organ damage. An understanding of the mechanisms responsible for homeostatic control of inflammation, which involve both innate and adoptive immune responses, will enable the development of novel therapies for SLE. Re...
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ژورنال
عنوان ژورنال: Japanese Journal of Clinical Immunology
سال: 2015
ISSN: 0911-4300,1349-7413
DOI: 10.2177/jsci.38.69